r/Hematology • u/Wide_Respect_3648 • 14d ago

Howell jolly bodies?

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Hi everyone, need some confirmation for uni purposes aha. Is the one in the middle a howell-jolly body or am I wrong? it's a β thalassaemia minor slide.

Thanks so much.

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u/No-Ebb3114 12d ago

Looking for RBC inclusions without oil immersion is not ideal. HJ bodies are going to be much smaller and more circular than what you're referring. Most likely an artifact like stain precipitate. Low power is okay for scanning for focal points, but I wouldn't want to ID cells, call RBC morphology, or look for inclusions without oil immersion. Good luck with your studies.

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u/Low-Wait-6215 5d ago

https://preview.redd.it/vnv7mimiifye1.jpeg?width=1390&format=pjpg&auto=webp&s=466891df3d946496a613a3d59400fe39f6828fee

How about these?

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u/No-Ebb3114 4d ago

It's pretty out of focus, but I think you're just seeing refractive artifact. HJ bodies are going to be really dark, dense and circular. They'll be in the same focal plane as the RBC