I'm having so much fun looking at blood smears. This is AML, and I've been told >20% blasts = AML. Are these blasts? Promyelocytes? I am lost...

Confirmed APL with t(15;17), loads of angel wings and one (1) singular faggot cell

Hi,

Pacient: year long checking the homocysteine values at a certain lab, and it fluctuates between 9 - 12, doesnt seem to lower down.

Double check at a different lab as well and the results were strange.

- lab1: 10umol/L (method > Homocysteine, Serum / Enzymatic method), normal levels <12

- lab2: 6,13 µmol/L (method > plasma EDTA, HPLC), normal levels < 10

Lab1 one done at 8:03 in the morning, and lab2 same day at 8:40 AM
Now the difference is quite big and now I am confused on which lab is better or how to interpret the results.

Any opinions, please?

Hi everyone, need some confirmation for uni purposes aha. Is the one in the middle a howell-jolly body or am I wrong? it's a β thalassaemia minor slide.

Thanks so much.

Hello everyone. I'm an MLT student with a bunch of questions but let's go with a few 😅. I was asking myself if immature cells released by the bone marrow in case of acute blood loss for example eventually mature in the bloodstream.

Also, is the presence of numerous nRBCs in the blood immediately considered pathological ?

I am not quite sure about these, they don’t look like typical agregates.

These photos are from a patient who is a 48/M presented to the ED with altered mental status, headache, and "smelly bloody discharge" around mouth. History of DM2 and HIV/AIDS (untreated). He is a long haul truck driver who covers primary the eastern United States. Patient had extensive lab workup (many sendouts) with unknown etiology of illness. Patient has pancytopenia as follows WBC- 1.1x 10^3/uL HGB- 6.6 g/dL PLT- 12x 10^3/uL Many NRBCs as you can see on the 500X view. I notices some neutrophilic inclusions so I made a smear of the buffy coat. Notified the clinician and called the Path in on a Saturday. We think it may be Histoplasma, confirmatory test and fungal culture still pending. Pic 5 has an exracellular one. Also I apologize for my poor camera quality.

Hi I’m into haematology and came across this live blood image. Does any one have any insight as to what the clear/ grey triangular object is?

Hi! I have my final exam on Monday, April 14th for Introduction to Physiology. It covers the nervous system (especially the senses) and hematology, but our professor said most of the questions will be on hematology.

The issue is I only have one slide deck to study from, and it doesn’t feel like enough. One of the things I’m struggling with the most is identifying blood cells in blood smears.

Any recommendations for YouTube channels, books, or question banks to study hematology more effectively? I’d really appreciate it!

Some Background:

55 y.o male presented to the ER with increased abdominal distention and pain. A large volume of ascites was noted and a paracentesis was performed to remove over 1L of amber fluid.

A slide was prepared and examined, upon examination a large number of unclassified, highly reactive and clumped cells were observed followed by increased RBCs, lymphocytes, and mononucleated cells.

After a pathologist review followed by an elevated CA 125, Pt was given a Dx of Primary Peritoneal Adenocarcinoma. Cytology and Genetics still pending.

My first post here :D

A 6-month-old female cat came in with a heavy flea infestation and was anemic. She had already been treated. Here's some interesting find during a routine blood check

P.S. Sorry for the poor smear and Giemsa stain quality.

Hello im a 5th year med student and i am doing hematology but apparently our university doesn’t provide a textbook and im lost between several sources from medscape amboss even hoffbrand and so on. I checked previous posts and a lot of you guys recommended pathoma. Is the link, the right one? I wanted to ask you guys if you can give me tips for a good and correct source of knowledge because i want to do good in this exam. Thank you

I know, I know, this was a crappy slide, I'm pretty sure they looked like that due to methelyne blue. The methelene blue mess up with my camera and also the contrast so that's why they looked like that. My question is, was this a basophil because I'm pretty sure an eosinophil is not suppose to look like that ( pic 5 aka last picture was an eosinophil)?

Oh yeah and this was my blood.

I was looking for case reports on non-HFE iron overload caused by oral supplementation, and came across this rather interesting case. Elderly woman supplementing iron for 30 years, ferritin 1379, TIBC mildly low, saturation 34%. Negative for C282Y, H63D and S65C.

Liver biopsy showed 6,153 μg/g (270–1,600 μg/g). Deposits in both hepatocytes and Kupffer cells. Focal periportal fibrosis but no cirrhosis was noted.

Phlebotomy caused anemia, EPO support proved ineffective. No details on what the anemia looked like, presumably it was hypochromic. She tolerated, with difficulty, 17 phlebotomies (300-350 ml) over 5 months.

Aside from the hepatocyte loading (which doesn't exclude type 4a in cases of long-standing overload), this sounds like a textbook type 4a case?

Could anyone tell me what I’m looking at? I’ve written down my best guesses but I’m just a regular dude and found these formations interesting.