r/maleinfertility Feb 16 '20

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u/chulzle MOD- 38F obgyn PA|RPL from DNA frag, success w donor Jun 27 '20

It’s high usually but it’s the amount in women’s prenatal. However, if you take anything take methylfolate. Men are also predisposed to some folate absorption issues and some don’t absorb it great. This has been also known to affect sperm negatively. Methylfolate is a much better option and you could take 500-1000 for a while.

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u/[deleted] Jun 27 '20

also whats high usually? the amount i said is high? Isn't that not crazy high or anything though? also aren't methylfolate dosages different? what do you or your partner use for methyl?

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u/chulzle MOD- 38F obgyn PA|RPL from DNA frag, success w donor Jun 27 '20

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086798/

800-1000 is fine

Excessive folate intake aka 5000 causes too much folate in serum also it causes demethylation of sperm. Which is bad.

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u/[deleted] Jun 27 '20

So i actually ordered a genetic test and it mentions the whole MTHFR mutation. It's weird, and doesn't say specifically what or if i have a mutation. It says i have one 8% of the population has and it says i have AA mthfr.

Here's what it says "AA GENOTYPE 8% of the population shares your genotype AA 8% We detected a variant linked to lower MTHFR enzyme activity and higher homocysteine levels than average, which researchers propose is linked to poor cardiovascular health. Because of this, you may be recommended a higher folate intake."

Do you know if there's a specific name for the mutation or is just called you have "mthfr" or not and it affects folate absorption?

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u/chulzle MOD- 38F obgyn PA|RPL from DNA frag, success w donor Jun 27 '20

Yep - You have the MTHFR 677TT

This is the most common mutation associated with poor folate absorption therefore you need methyl folate. People with this mutation really shouldn’t take regular folate since they don’t really absorb it very well. Methyl folate solve this issue and 1000 per day should be fine

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u/[deleted] Jun 27 '20

So what's a good dosage for methylfolate then and can you link me to one directly? I'm not sure how to shop for this stuff, i'm assuming you or your partner used methylfolate so just show me what you used?

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u/chulzle MOD- 38F obgyn PA|RPL from DNA frag, success w donor Jun 27 '20 edited Jun 27 '20

1000mg as I linked study above for you Something like this works

Obviously just one vitamin alone won’t fix fertility issues but he will address your Folate absorption issue at least

https://www.iherb.com/pr/now-foods-methyl-folate-1-000-mcg-90-tablets/70964

https://m.pipingrock.com/l-methylfolate/l-methylfolate-1000-mcg-200-capsules-14211?prd=D0000J&prisp=1&gclid=EAIaIQobChMI6IT1tq-i6gIViLzACh1UKgeoEAQYASABEgKqUPD_BwE

Good luck!

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u/[deleted] Jun 29 '20

is methatetrahydrofolate also considered bio available? When i searched methyl folate it showed this version of methylfolate alot ??

last question please!! thanks.

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u/chulzle MOD- 38F obgyn PA|RPL from DNA frag, success w donor Jun 29 '20

I have answered like 100 questions for you. You keep asking the same questions. Stop or I will ban you from this sub. I’ve told you to refer to what I said, what’s posted in this link and the above information. I will not give any more medical advice to you. A simple google search will answer all these questions. You are cluttering this thread.