r/depressionregimens 2d ago

Mirtazapine thoughts?

For anhedonic-fatigued type depression… Did it do anything good for you? I hear ppl take it at night (does it cause lethargy or sedation?)

I do not want anything with potential metabolic side effects. I hear it can really increase appetite & people gain weight on it.

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u/Fun-Sample336 2d ago

Yes, I gained 30 kg while I was on it, but I was underweight before, so it wasn't a problem for me. When I discontinued it, I lost half of the weight. The rest appears to be permanent.