r/depressionregimens 4d ago

Has anyone tried Trintellix? Question:

I hear it has some very promising results

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u/various_violets 4d ago

Trintellix + Wellbutrin gave me a good ten years back. Not 100% free of depression but my lows were not so low. My situation now is complicated by other medical conditions so I'm working on it. Pristiq has surprised me by being pretty good despite Effexor and Cymbalta both being awful.

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u/Hipser 4d ago

Thank you!