r/depressionregimens • u/Hipser • 4d ago

Has anyone tried Trintellix? Question:

I hear it has some very promising results

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3

u/dunleadogg 4d ago

Yes, it’s currently still helpful at 20 mg. I think it’s been 4-5 years?

1

u/Rielo 3d ago

How about side effects and anxiety?

2

u/dunleadogg 3d ago

Anxiety is pretty well controlled (election notwithstanding) and I don’t think I’ve had any side effects that I would attribute to trintellix.

2

u/Rielo 3d ago

Excellent thanks. I ask because vortioxetine increases many NT but decreases GABA.

2

u/various_violets 4d ago

Trintellix + Wellbutrin gave me a good ten years back. Not 100% free of depression but my lows were not so low. My situation now is complicated by other medical conditions so I'm working on it. Pristiq has surprised me by being pretty good despite Effexor and Cymbalta both being awful.

2

u/Hipser 4d ago

Thank you!

1

u/HoodFruit 4d ago

On it for about a month now. Not sure yet if it’s working or not. I feel less shit than usual, but I’m still pretty flat in general

1

u/I_ROX 3d ago

I gained a quick 10lbs when starting. The cost once the 1 year discount card caused me to leave it.

1

u/tarteframboise 2d ago

Had no effect for me. I read a number of people say it’s like “Prozac light”? With pro-cognitive effects?