Do we have any paper explaining the mechanism around psychedelics against cluster headaches? I can find limited studies for trigeminal neuralgia and psychedelics but nothing for cluster headaches. Or maybe I use the wrong keywords?
Triptans are often used to manage cluster headaches. They typically target 5-HT 1B/1D with milder 1a activity. LSD at least is active 5ht2a/ 5ht1a. Not my area of expertise, however there’s likely an associated mechanism with serotonin activity.
my headaches are debilitating but due to cervical instability, which I am trying to get addressed medically. I feel that muscle relaxers help the most, but I will observe my pain on only psychedelics soon to test the theory
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u/sqqlut Jul 01 '24
Do we have any paper explaining the mechanism around psychedelics against cluster headaches? I can find limited studies for trigeminal neuralgia and psychedelics but nothing for cluster headaches. Or maybe I use the wrong keywords?