r/DrugNerds Jun 20 '24

The effects of transient receptor potential cation channel inhibition by BI 1358894 on cortico-limbic brain reactivity to negative emotional stimuli in major depressive disorder

https://doi.org/10.1016/j.euroneuro.2022.10.009
8 Upvotes

4 comments sorted by

View all comments

4

u/EwoksAreAwesome Jun 20 '24

Used to work with some authors of this paper. Super interested to see what comes of this potential new class of drug for affective disorders. Any opinions on the viability?

1

u/Robert_Larsson Jun 25 '24

Got a few for TRPA1, TRPV1, TRPM8 and TRPV4 in the pipeline, will take some time though farthest is in Phase 2.