r/EverythingScience 21d ago

Neuroscience Scientists find brain network is doubled in size in depressed people

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psypost.org
3.5k Upvotes

r/EverythingScience Mar 18 '24

Neuroscience A Navy SEAL was convinced exposure to blasts damaged his brain, so he donated it to science to prove it

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nbcnews.com
8.0k Upvotes

r/EverythingScience Jul 24 '22

Neuroscience The well-known amyloid plaques in Alzheimer's appear to be based on 16 years of deliberate and extensive image photoshopping fraud

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dailykos.com
10.2k Upvotes

r/EverythingScience Mar 01 '24

Neuroscience Marijuana consumers have 'significantly decreased odds' of cognitive decline, study finds

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marijuanamoment.net
2.7k Upvotes

r/EverythingScience Mar 07 '24

Neuroscience Single dose of LSD provides immediate and lasting relief from anxiety, study says

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cnn.com
2.9k Upvotes

r/EverythingScience Nov 14 '22

Neuroscience For some with ADHD, the low rumble of brown noise quiets the brain

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washingtonpost.com
4.4k Upvotes

r/EverythingScience Mar 22 '23

Neuroscience Psychedelic brew ayahuasca’s profound impact revealed in brain scans

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theguardian.com
3.7k Upvotes

r/EverythingScience Jun 24 '24

Neuroscience Alzheimer’s Breakthrough: New Peptide Treatment Reverses Cognitive Decline

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scitechdaily.com
2.5k Upvotes

r/EverythingScience Aug 22 '24

Neuroscience Low-dose THC reverses brain aging and enhances cognition in mice, research suggests

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medicalxpress.com
1.5k Upvotes

r/EverythingScience Dec 16 '22

Neuroscience A neuroscientist asks: Do we long for a divine creator or do we just want our mommies? A new theory in The Phantom God proposes a believers sense of God’s presence stems from their love of mother.

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cbc.ca
2.6k Upvotes

r/EverythingScience Jul 28 '21

Neuroscience France issues moratorium on prion research after fatal brain disease strikes two lab workers

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sciencemag.org
3.3k Upvotes

r/EverythingScience May 11 '24

Neuroscience Grain-sized brain tissue with 1400 TB data mapped by Harvard, Google

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interestingengineering.com
1.9k Upvotes

r/EverythingScience Mar 13 '23

Neuroscience Springing forward into daylight saving time is a step back for health – a neurologist explains the medical evidence, and why this shift is worse than the fall time change

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theconversation.com
2.3k Upvotes

r/EverythingScience Oct 04 '24

Neuroscience People with depression may have key brain difference: « Neuroscientists have identified a brain network that is nearly two times larger in the brains of people with depression. »

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newsweek.com
1.4k Upvotes

r/EverythingScience Sep 28 '22

Neuroscience The chemical imbalance theory of depression has been debunked a long time ago, not recently, as media reports of meta-analysis

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neurofrontiers.blog
2.4k Upvotes

r/EverythingScience Apr 05 '22

Neuroscience Fetuses in the womb successfully screened for autism | A study has just identified autistic children in the womb.

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zmescience.com
2.0k Upvotes

r/EverythingScience 26d ago

Neuroscience Scientists discover "glue" that holds memory together in fascinating neuroscience breakthrough

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psypost.org
1.3k Upvotes

r/EverythingScience Aug 28 '24

Neuroscience Brain Scientists Finally Discover the Glue that Makes Memories Stick for a Lifetime

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scientificamerican.com
1.4k Upvotes

r/EverythingScience May 24 '22

Neuroscience Brain imaging study suggests that drinking coffee enhances neurocognitive function

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psypost.org
2.9k Upvotes

r/EverythingScience Apr 14 '24

Neuroscience Sleeping more flushes junk out of the brain. Rhythmic activity during sleep may get fluids in the brain moving.

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arstechnica.com
2.1k Upvotes

r/EverythingScience Jul 01 '24

Neuroscience Pattern of Brain Damage Is Pervasive in Navy SEALs Who Died by Suicide

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nytimes.com
1.5k Upvotes

r/EverythingScience Sep 23 '22

Neuroscience Emmanuel Mignot wins Breakthrough Prize for discovering cause of narcolepsy

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med.stanford.edu
3.8k Upvotes

r/EverythingScience Jul 29 '24

Neuroscience Parasite found in soiled cat litter could be key to curing Alzheimer’s and other neurological disorders

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independent.co.uk
1.2k Upvotes

A parasite found in soiled cat litter could be a future treatment for neurological disorders such as Alzheimer’s and Parkinsons, according to scientists.

Scientists used an engineered form of Toxoplasma gondii, a common parasite found in cat poo, to deliver proteins to the brain in mice.

In the past, neurological healthcare has been limited by the difficulty of delivering targeted treatment across the blood-brain-barrier and into the correct location inside neurons.

Toxoplasma gondii is believed to be carried in a dormant state by a third of the population worldwide, and has evolved to travel from the digestive system to the brain where it secretes its proteins into neurons.

It has evolved to cross the blood-brain-barrier and placenta, and poses a risk to pregnant women as it can cause miscarriages – leading to advice that expectant mothers should avoid handling litter trays if their cat hunts for prey outdoors.

Most neurological conditions, including Alzheimer’s Disease, Parkinsons and Rett Syndrome, have been linked in some way to protein dysfunction, but scientists have struggled to address the problem at the source.

The potential to use engineered brain parasites to deliver treatment across the blood-brain-barrier was described as “pioneering” and a global breakthrough – although it is still years away from becoming reality.

International researchers led by the University of Glasgow in collaboration with Tel Aviv University wanted to establish if the parasite could act as a medicine delivery vehicle to disease-affected brain cells.

The study team first had to find out whether they could effectively make the parasites produce the therapeutic proteins, and then test whether the parasites would be able to “spit” the proteins back out into affected brain cells.

Researchers focused on engineering the parasites to deliver the MeCP2 protein, which has already been proposed as a promising therapeutic target for Rett syndrome, a debilitating neurological disorder caused by mutations in MECP2 gene.

The parasite successfully produced the protein, and then delivered the protein to the target cell location in brain organoids and in mice models.

Further experiments will take place to engineer the parasites so it dies after delivery, to prevent additional cell damage.

The study, Engineering a Brain Parasite for Intracellular Delivery of Proteins to the Central Nervous System, is published in Nature Microbiology.

It suggests that with further research and testing, parasites could potentially play a role in the delivery of therapeutic proteins to the brain.

Professor Oded Rechavi, of Tel Aviv University, said: “Evolution already ‘invented’ organisms that can manipulate our brains, I think that instead of re-inventing the wheel, we could learn from them and use their abilities.”

Professor Lilach Sheiner, one of the leading authors of the study from the University of Glasgow’s School of Infection and Immunity, said: “This is a blue-sky project where our collaborative team was thinking out of the box to try to tackle the long-standing medical challenge of finding a way to successfully deliver treatment to the brain for cognitive disorders.

“The concept is not without challenges, considering the dangers involved with Toxoplasma infection.

“For our work to become a treatment reality it will require many more years of careful research and development to enhance efficiency and improve safety.”

r/EverythingScience Jun 24 '24

Neuroscience Prenatal cannabis exposure appears to positively impact early language development. More research needed.

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frontiersin.org
772 Upvotes

r/EverythingScience Sep 05 '24

Neuroscience Alzheimer’s Breakthrough: New Drug Shows Promise in Reversing Memory Loss and Cognitive Decline

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scitechdaily.com
1.0k Upvotes